Porcine Health Management

Chosen Topics:

Immunology and Vaccinology

31 - 45 of 46

IMMUNOGENIC POTENTIAL OF A SALMONELLA TYPHIMURIUM LIVE VACCINE FOR PIGS AGAINST MONOPHASIC SALMONELLA TYPHIMURIUM DT 193

Monophasic S. Typhimurium (mSTm) strains derived from pork have an increasing zoonotic importance in humans. The <i>S.</i> Typhimurium (STm) live vaccine SALMOPORC (IDT Biologika GmbH) has proven to be successful in combating STm infections in pigs. This...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

KINETICS AND IMMUNOGLOBULIN SUBTYPING OF MATERNALLY-DERIVED ANTIBODIES AFTER VACCINATION OF GILTS WITH A SALMONELLA TYPHIMURIUM LIVE VACCINE

SALMOPORC (IDT Biologika GmbH) is a S.Typhimurium live vaccine for pigs licensed for oral (piglets) and subcutaneous (sows) application. The antibody kinetics evoked by each administration route have been studied so far, but knowledge about the maternal...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

EFFECT OF THREE ADJUVANTS USED FOR AUTOVACCINE PRODUCTION AGAINST ACTINOBACILLUS PLEUROPNEUMONIAE ON SEROLOGICAL PARAMETERS WHEN USED ON FIELD

Actinobacillus pleuropneumoniae (App) Autovaccine is complementary to the commercial vaccines in herds with recurrent troubles. Extent of inflammatory response and subsequent immunization is influenced by the chosen adjuvant. In this study, different...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

SAFETY OF THREE ADJUVANTS USED FOR AUTOVACCINE PRODUCTION AGAINST ACTINOBACILLUS PLEUROPNEUMONIAE: A FIELD EVALUATION ON FATTENERS

Among alternatives to antibacterial treatments, autovaccines remain a relevant customized solution in herds affected by Actinobacillus pleuropneumoniae (App). In this trial, different formulations are tested (with and without antigen) to assess secondary...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

LIMITATIONS OF USING HISTORICAL COMPARISON TO ASSESS VACCINE EFFICACY AND THE VALUE OF DIAGNOSTIC DATA.    

For many producers the only practical way to assess the impact of any change is by comparing the performance of successive batches of pigs.  This example illustrates the potential limitations of this approach as well as the value of diagnostic data in...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

SEROLOGICAL RESPONSE TO M.HYOPNEUMONIAE AFTER VACCINATION OF BREEDING GILTS WITH SUVAXYN® CIRCO + MH RTU OR PORCILIS® PCV M HYO AT 3 WEEKS OF AGE. ...

Future breeding gilts are often vaccinated as piglets against both Circovirus and M. hyopneumoniae.  Later, typically before moving at around 12 weeks of age, it may be desirable to confirm low or absent M. hyopneumoniae infection by demonstrating a...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

SURVEY OF PORCINE LUNG LESIONS AT SLAUGHTER FROM BATCHES VACCINATED WITH DIFFERENT MYCOPLASMA HYOPNEUMONIAE VACCINES

Piglet vaccination against Mycoplasma hyopneumoniae (M.hyo) is an effective method to tackle enzootic pneumonia (EP), reducing clinical signs and improving performance. The aim of this study was to compare lung lesions at slaughter from pigs vaccinated...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

EFFICACY OF THREE COMMERCIAL LIVE VACCINES AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) IN WEANED PIGLETS.

Vaccines against PRRSV are useful to: 1) reduce clinical signs, 2) improve zootechnical parameters and 3) decrease virus transmission. In the present study, the efficacy of three PRRSV1 live vaccines were compared in a PRRSV1 challenge model of weaned...
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

A RECOMBINATION BETWEEN TWO GENOTYPE 1 PRRSV MODIFIED LIVE VACCINES RESULTS IN A FIELD STRAIN WITH INCREASED VIRULENCE  

Introduction In Europe, modified live vaccines of genotype 1 (MLV1) are commonly used to control PRRSV infection in swine herds. In December 2014, following successive implementation of a PRRS vaccination program with VP-046BIS and DV strains in a farm, a recombinant strain from the 2 vaccines was isolated. In order to assess the virulence of the recombinant strain, we set-up an in vivo study to compare clinical, virological and transmission parameters with the 2 parental MLV1 strains.  
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

NOVEL INFLUENZA VACCINE EFFICACY AND SAFETY ESTABLISHED FOR NEWBORN PIGS

Introduction. Economic losses due to swine influenza (IAV-S) are substantial and a global problem, ranking among the top three major health challenges in the swine industry. Historic control strategies include the use of killed virus (KV) vaccines in breeding females to confer passive immunity to offspring, however effective protection requires KV vaccine and challenge virus to be closely related. Live attenuated influenza virus (LAIV) vaccines present an important platform with advantages to stimulate both cell-mediated and mucosal immunity. Boehringer Ingelheim has licensed a bivalent IAV-S (H1N1 and H3N2) LAIV vaccine (Ingelvac ProvenzaTM).  
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

MATERNALLY DERIVED ANTIBODIES REDUCE VACCINE EFFICACY AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME

Introduction Modified live vaccines (MLV) are commonly used to reduce the impact of Porcine Reproductive and Respiratory Syndrome (PRRS) but limited efficacy is achieved in field conditions. We recently showed that maternally-derived neutralizing antibodies (MDNA) impair piglet immune response to vaccination. Here, we evaluated the impact of MDNA on vaccine efficacy against PRRS virus (PRRSV) challenge.  
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

MATERNALLY DERIVED IMMUNITY IN PIGS. EXPLORING ITS MANAGEMENT THROUGH THE IMMUNOCRIT ASSAY.

Introduction Colostrum intake is crucial for piglet survival and a critical point in the health management of swine farms because it is the main known transmission mechanism of maternal derived immunity (MDI). The immunocrit assay has been suggested as a cost effective method to quantitatively evaluate maternal antibodies in piglets after colostrum intake. The objective of this study was to describe the immunocrit values in farms with high health status and good productive performances.
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

VACCINATION OF 1 DAY-OLD PIGS WITH A PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) MODIFIED LIVE ATTENUATED VACCINE IS ABLE TO OVERCOME MATERNAL IMMUNITY  

Introduction PRRSV is known to circulate after weaning in unstable pig farms. Having immunity in place when piglets are weaned can protect them from early infections. Due to the effect of maternally derived immunity in newborns, vaccination is usually delayed until immunity vanishes, at 3-4 weeks of age. Since onset of immunity against PRRSV takes at least 4 weeks to develop, animals can have a period of risk for PRRSV infection, in which maternal immunity is no longer acting, and vaccine immunity has not yet developed. Suvaxyn PRRS MLV is the first vaccine licensed in Europe which is able to overcome maternal immunity. 
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

EFFICACY OF AN AUTOGENOUS VACCINE AGAINST BRACHYSPIRA HYODYSENTERIAE

Introduction Swine Dysentery (SD) results from infection of the large intestine with Brachyspira hyodysenteriae (B.hyodysenteriae). A commercial vaccine against SD is not available in Europe, but autogenous vaccines may be used. However, there is little scientific evidence for their efficacy.  
Type
Abstract
Year
2018
Topic
Immunology and Vaccinology

Pathogenesis comparison and cross-protection efficacy of the U.S. PEDV prototype and SINDEL-variant strains in weaned pigs

Two strains (U.S. prototype [P] and S-INDEL-variant [V]) of PEDV are currently circulating in the U.S. Pathogenesis comparison of the two strains in 5-day-old pigs showed that the V-strain was less virulent than the P-strain. However, PEDV pathogenicity is age dependent. Also, understanding the cross-protection between two strains is imperative for PEDV vaccine development. In the current study, the pathogenesis difference and the cross-protection efficacy between the two U.S. PEDV strains were evaluated in weaned pigs.
Type
Abstract
Year
2016
Topic
Immunology and Vaccinology